Prostatitis is a common disease of adult men, with a incidence rate of about 9% and a prevalence rate of 12%, covering all ages. The etiology and pathogenesis of chronic non bacterial prostatitis are complex and difficult to diagnose and treat. Developing a well prepared animal model is an effective method for elucidating the pathogenesis of this disease and developing new drugs.
Carrageenan is an inflammatory substance extracted from plants. Its inflammatory mechanism is mainly to increase local prostaglandin synthesis and induce edema with vasoactive peptides and kinins, leading to chronic inflammation at the injection site.
Observation indicators
The white blood cell content increases in blood and urine routine, and there is infiltration of interstitial or glandular inflammatory cells in the prostate.
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