The lens is a special organ whose cells are differentiated from epithelial cells and have no blood vessels or nerves. It can only absorb nutrients from the surrounding aqueous humor. Cataracts manifest as specific areas of the lens or complete opacity. The damage to the microstructure of the lens interferes with the transmission of light to the retina, causing visual impairment. This disease is the world's leading cause of blindness. Therefore, constructing a cataract model is crucial for studying the pathogenesis of cataracts and finding drugs for treating cataracts.
Observation indicators
Measurement of lens opacity, biochemical methods for measuring superoxide dismutase (SOD) and glutathione peroxidase (GSH Px), malondialdehyde (MDA), total antioxidant capacity (TAC) in the crystalline body.
Partial experimental diagram display