Chronic heart failure (CHF) is a common clinical syndrome that occurs when a variety of different harmful factors stimulate enough to cause myocardial dysfunction. It is characterized by high incidence rate, high hospitalization rate, and high mortality. Among the many methods for establishing CHF models nowadays, abdominal aortic constriction has become a commonly used model in CHF experimental research due to its economy, practicality, and relatively simple operation. The model induced by abdominal aortic constriction can simulate the pathological process of clinical chronic congestive heart failure.

Observation indicators

he model group had fluffy, dry and dull fur, increased respiratory rate, increased myocardial cell volume, decreased quantity, and disorderly arrangement; The pathological changes are obvious, such as an increase in myocardial interstitial collagen fibers and an increase in extracellular matrix around blood vessels.

Partial Results Display